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Interleukin-1 Receptor Associated Kinase 3 (IRAK3) Antibody
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Catalogue No: abx146630
Price:
US$406.00
(Size: 100 µg)
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Interleukin-1 Receptor Associated Kinase 3 (IRAK3) Antibody is a Rabbit Polyclonal antibody for the detection of IRAK-3. This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Research Articles on Interleukin-1 Receptor Associated Kinase 3 (IRAK3)
| Target | Interleukin-1 Receptor Associated Kinase 3 (IRAK3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | IRAK3 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | Q9Y616 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DQ57 |
| UniProt Entry Name | IRAK3_HUMAN |
| Gene Symbol | IRAK3 |
| GeneID | 11213 |
| OMIM | 604459 |
| HGNC | 17020 |
| Ensembl | ENSG00000090376 |
| String | 9606.ENSP00000261233 |
| Molecular Weight | Observed MW: 68 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |