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Interferon Regulatory Factor 4 (IRF4) Antibody
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Catalogue No: abx000976
Price:
US$217.50
(Size: 20 µl)
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IRF4 Antibody is a Rabbit Polyclonal antibody against IRF4. The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
Research Articles on Interferon Regulatory Factor 4 (IRF4)
| Target | Interferon Regulatory Factor 4 (IRF4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 180-451 of human IRF4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15306 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5VUI7, Q99660 |
| UniProt Entry Name | IRF4_HUMAN |
| Gene Symbol | IRF4 |
| GeneID | 3662 |
| NCBI Accession | NP_002451.2 |
| KEGG | hsa:3662 |
| String | 9606.ENSP00000370343 |
| Molecular Weight | Calculated MW: 52 kDa Observed MW: 52 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |