Interferon Regulatory Factor 6 (IRF6) Antibody

IRF6 Antibody is a Rabbit Polyclonal antibody against IRF6. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Target	Interferon Regulatory Factor 6 (IRF6)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 115-300 of human IRF6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O14896 (UniProt, ExPASy)
UniProt Secondary AC	B4DLE2, D3DT90, F5GWX8, G0ZTL0
UniProt Entry Name	IRF6_HUMAN
Gene Symbol	IRF6
GeneID	3664
NCBI Accession	NP_006138.1
KEGG	hsa:3664
String	9606.ENSP00000355988
Molecular Weight	Calculated MW: 53 kDa Observed MW: 53 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Interferon Regulatory Factor 6 (IRF6)

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