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Interferon Regulatory Factor 8 (IRF8) Antibody
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Catalogue No: abx004441
Price:
US$203.00
(Size: 20 µl)
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IRF8 Antibody is a Rabbit Polyclonal antibody against IRF8. Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Research Articles on Interferon Regulatory Factor 8 (IRF8)
| Target | Interferon Regulatory Factor 8 (IRF8) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 137-426 of human IRF8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q02556 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AV82 |
| UniProt Entry Name | IRF8_HUMAN |
| Gene Symbol | IRF8 |
| GeneID | 3394 |
| NCBI Accession | NP_002154.1 |
| KEGG | hsa:3394 |
| String | 9606.ENSP00000268638 |
| Molecular Weight | Calculated MW: 48 kDa Observed MW: 50 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |