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Insulin Receptor Substrate 2 (IRS2) Antibody
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Catalogue No: abx033681
Price:
US$326.25
(Size: 80 µl)
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Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Research Articles on Insulin Receptor Substrate 2 (IRS2)
| Target | Insulin Receptor Substrate 2 (IRS2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1309-1338 amino acids from the C-terminal region of human IRS2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y4H2 (UniProt, ExPASy) |
| UniProt Secondary AC | Q96RR2, Q9BZG0, Q9Y6I5 |
| UniProt Entry Name | IRS2_HUMAN |
| String | 9606.ENSP00000365016 |
| Molecular Weight | Calculated MW: 137 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |