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IRS2 (pY978) Antibody
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Catalogue No: abx032045
Price:
US$326.25
(Size: 80 µl)
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Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Research Articles on IRS2 (pY978)
| Target | IRS2 (pY978) |
| Clonality | Polyclonal |
| Target Modification | Tyr978 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y978 of human IRS2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y4H2 (UniProt, ExPASy) |
| UniProt Secondary AC | Q96RR2, Q9BZG0, Q9Y6I5 |
| UniProt Entry Name | IRS2_HUMAN |
| String | 9606.ENSP00000365016 |
| Molecular Weight | Calculated MW: 137 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse IRS2. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |