Iscalimab

Iscalimab is a monoclonal antibody biosimilar expressed in CHO cells, targeting CD40/TNFRSF5, for use in laboratory research applications. This product is not suitable for use as medicines or in human, therapeutic or diagnostic applications.

Iscalimab (CFZ533) is a new, fully humanized monoclonal antibody that targets cluster of differentiation 40 (CD40), which can regulate the CD40-CD154 costimulatory pathway and prevent CD40 pathway signal transduction and CD40+ cell type activation. It is expected Become a new treatment for solid organs and related autoimmune diseases.

Target	CD40/TNFRSF5
Clonality	Monoclonal
Reactivity	Human
Expression	Recombinant
Tested Applications	ELISA, WB
Host	Human
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Isotype	IgG1 Kappa
Form	Liquid
Purity	> 95%
Purification	Purified from cell culture supernatants by Protein A/G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Buffer	0.01 M PBS. pH 7.4.
CAS Number	2031153-61-2
Concentration	Batch-dependent, typically between 0.5-2.0 mg/ml.
Availability	Shipped within 7-12 working days.
Note	This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Research Articles on CD40/TNFRSF5

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue