Insulin Gene Enhancer Protein ISL-1 (ISL1) Antibody

ISL1 Antibody is a Rabbit Polyclonal antibody against ISL1. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Target	Insulin Gene Enhancer Protein ISL-1 (ISL1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-349 of human Islet1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P61371 (UniProt, ExPASy)
UniProt Secondary AC	P20663, P47894
UniProt Entry Name	ISL1_HUMAN
Gene Symbol	ISL1
GeneID	3670
NCBI Accession	NP_002193.2
KEGG	hsa:3670
String	9606.ENSP00000230658
Molecular Weight	Calculated MW: 39 kDa Observed MW: 50 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Insulin Gene Enhancer Protein ISL-1 (ISL1)

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