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Integrin Alpha 1 (ITGA1) Antibody
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Catalogue No: abx034116
Price:
US$290.00
(Size: 80 µl)
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Integrin Alpha 1 (ITGA1) is the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
Research Articles on Integrin Alpha 1 (ITGA1)
| Target | Integrin Alpha 1 (ITGA1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 727-755 amino acids from the Central region of human ITGA1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P56199 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RNU0 |
| UniProt Entry Name | ITA1_HUMAN |
| KEGG | hsa:3672 |
| String | 9606.ENSP00000282588 |
| Molecular Weight | Calculated MW: 131 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Recognizes proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |