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Integrin Alpha IIb / CD41 (ITGA2B) Antibody
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Catalogue No: abx004343
Price:
US$217.50
(Size: 20 µl)
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ITGA2B Antibody is a Rabbit Polyclonal antibody against ITGA2B. ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Research Articles on Integrin Alpha IIb / CD41 (ITGA2B)
| Target | Integrin Alpha IIb / CD41 (ITGA2B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 693-993 of human CD41/CD41/ITGA2B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P08514 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RCY8, O95366, Q14443, Q17R67 |
| UniProt Entry Name | ITA2B_HUMAN |
| Gene Symbol | ITGA2B |
| GeneID | 3674 |
| NCBI Accession | NP_000410.2 |
| KEGG | hsa:3674 |
| String | 9606.ENSP00000262407 |
| Molecular Weight | Calculated MW: 113 kDa Observed MW: 135 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |