+44 (0) 1223 755950
+1 832 327 7413
Integrin Alpha 8 (ITGA8) Antibody
REQUEST MORE INFO
Catalogue No: abx026339
Price:
US$326.25
(Size: 80 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
Research Articles on Integrin Alpha 8 (ITGA8)
| Target | Integrin Alpha 8 (ITGA8) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P53708 (UniProt, ExPASy) |
| UniProt Secondary AC | B0YJ31, Q5VX94 |
| UniProt Entry Name | ITA8_HUMAN |
| KEGG | hsa:8516 |
| String | 9606.ENSP00000367316 |
| Molecular Weight | Calculated MW: 117 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |