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Integrin Alpha X / CD11C (ITGAX) Antibody
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Catalogue No: abx033098
Price:
US$290.00
(Size: 80 µl)
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ITGAX is the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
Research Articles on Integrin Alpha X / CD11C (ITGAX)
| Target | Integrin Alpha X / CD11C (ITGAX) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1119-1145 amino acids from the C-terminal region of human ITGAX. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P20702 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8IVA6 |
| UniProt Entry Name | ITAX_HUMAN |
| Gene Symbol | ITGAX |
| KEGG | hsa:3687 |
| String | 9606.ENSP00000454623 |
| Molecular Weight | Calculated MW: 128 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |