Integrin Beta 4 (ITGb4) Antibody

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Catalogue No: abx015900
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors.Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities.Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth.This gene encodes the integrin beta 4 subunit, a receptor for the laminins.This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma.Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia.Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Target Integrin Beta 4 (ITGb4)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. coli.
Isotype IgG1
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16144 (UniProt, ExPASy)
UniProt Entry Name ITB4_HUMAN
Gene Symbol ITGB4
GeneID 3691
OMIM 131800
HGNC 6158
KEGG hsa:3691
Ensembl ENSG00000132470
String 9606.ENSP00000200181
Molecular Weight 202 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Integrin Beta 4 (ITGb4)


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