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Integral Membrane Protein 2C (ITM2C) Antibody
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Catalogue No: abx029346
Price:
US$290.00
(Size: 80 µl)
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Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
Research Articles on Integral Membrane Protein 2C (ITM2C)
| Target | Integral Membrane Protein 2C (ITM2C) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITM2C. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9NQX7 (UniProt, ExPASy) |
| UniProt Entry Name | ITM2C_HUMAN |
| Gene Symbol | ITM2C |
| String | 9606.ENSP00000322730 |
| Molecular Weight | Calculated MW: 30.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey ITM2C. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |