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Tyrosine-Protein Kinase JAK3 (JAK3) Antibody
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Catalogue No: abx011029
Price:
US$420.50
(Size: 100 µl)
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Tyrosine-Protein Kinase JAK3 (JAK3) Antibody is a mouse monoclonal against Tyrosine-Protein Kinase JAK3 (JAK3). It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
Research Articles on Tyrosine-Protein Kinase JAK3 (JAK3)
| Target | Tyrosine-Protein Kinase JAK3 (JAK3) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human JAK3 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P52333 (UniProt, ExPASy) |
| UniProt Secondary AC | Q13259, Q13260, Q13611, Q8N1E8, Q99699, Q9Y6S2 |
| UniProt Entry Name | JAK3_HUMAN |
| GeneID | 3718 |
| KEGG | hsa:3718 |
| String | 9606.ENSP00000391676 |
| Enzyme Commission Number | EC 2.7.10.2 |
| Molecular Weight | 125 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |