C-Jun-Amino-Terminal Kinase-Interacting Protein 1 / JIP1 (MAPK8IP1) Antibody

JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.

Target	C-Jun-Amino-Terminal Kinase-Interacting Protein 1 / JIP1 (MAPK8IP1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 470-498 amino acids from the C-terminal region of human JIP1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UQF2 (UniProt, ExPASy)
UniProt Secondary AC	D3DQP4, O43407
UniProt Entry Name	JIP1_HUMAN
Gene Symbol	MAPK8IP1
String	9606.ENSP00000241014
Molecular Weight	Calculated MW: 77.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on C-Jun-Amino-Terminal Kinase-Interacting Protein 1 / JIP1 (MAPK8IP1)

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