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C-Jun-Amino-Terminal Kinase-Interacting Protein 1 / JIP1 (MAPK8IP1) Antibody
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Catalogue No: abx034197
Price:
US$326.25
(Size: 80 µl)
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JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.
Research Articles on C-Jun-Amino-Terminal Kinase-Interacting Protein 1 / JIP1 (MAPK8IP1)
| Target | C-Jun-Amino-Terminal Kinase-Interacting Protein 1 / JIP1 (MAPK8IP1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 470-498 amino acids from the C-terminal region of human JIP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UQF2 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DQP4, O43407 |
| UniProt Entry Name | JIP1_HUMAN |
| Gene Symbol | MAPK8IP1 |
| String | 9606.ENSP00000241014 |
| Molecular Weight | Calculated MW: 77.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |