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Jumonji Domain-Containing Protein 2B (JMJD2B) Antibody
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Catalogue No: abx034447
Price:
US$290.00
(Size: 80 µl)
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Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Research Articles on Jumonji Domain-Containing Protein 2B (JMJD2B)
| Target | Jumonji Domain-Containing Protein 2B (JMJD2B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 281-306 amino acids from human JMJD2B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O94953 (UniProt, ExPASy) |
| UniProt Secondary AC | B9EGN8, D6W631, O75274, Q6P3R5, Q9P1V1, Q9UF40 |
| UniProt Entry Name | KDM4B_HUMAN |
| Gene Symbol | KDM4B |
| KEGG | hsa:23030 |
| String | 9606.ENSP00000159111 |
| Molecular Weight | Calculated MW: 122 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |