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Jumonji Domain-Containing Protein 2C (JMJD2C) Antibody
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Catalogue No: abx026266
Price:
US$326.25
(Size: 80 µl)
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This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
Research Articles on Jumonji Domain-Containing Protein 2C (JMJD2C)
| Target | Jumonji Domain-Containing Protein 2C (JMJD2C) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, FCM: 1/25. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 1023-1056 amino acids from the C-terminal region of human JMJD2C. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9H3R0 (UniProt, ExPASy) |
| UniProt Entry Name | KDM4C_HUMAN |
| Gene Symbol | KDM4C |
| String | 9606.ENSP00000370710 |
| Molecular Weight | Calculated MW: 120 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |