Kallikrein 2 (KLK2) Antibody

Kallikreins are a group of serine proteases manifesting diverse physiological functions. The glandular kallikreins are a distinct group of serine proteases with an ability to release vasoactive peptides from kininogen in vitro, although the kininogenase activity of different kallikreins is highly variable. Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Many kallikrein genes are differentially expressed in various malignancies. Human glandular kallikrein (hK2; encoded by the KLK2 gene) is an emerging tumor marker for prostate cancer.

Target	Kallikrein 2 (KLK2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 166-197 amino acids from the C-terminal region of human Kallikrein 2 (KLK2).
Isotype	IgG
Form	Liquid
Purification	Purified by saturated ammonium sulfate (SAS) precipitation followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P20151 (UniProt, ExPASy)
UniProt Secondary AC	B4DU93, B4DUB0, F5H8L3, Q15946, Q9UJZ9
UniProt Entry Name	KLK2_HUMAN
Gene Symbol	KLK2
KEGG	hsa:3817
String	9606.ENSP00000313581
Molecular Weight	Calculated MW: 28.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Kallikrein 2 (KLK2)

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