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Lysyl-tRNA Synthetase (KARS) Antibody
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Catalogue No: abx011059
Price:
US$420.50
(Size: 100 µl)
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KARS: lysyl-tRNA synthetase. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Research Articles on Lysyl-tRNA Synthetase (KARS)
| Target | Lysyl-tRNA Synthetase (KARS) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of KARS (aa90-174) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q15046 (UniProt, ExPASy) |
| UniProt Secondary AC | A8MSK1, D3DUK4, O14946, Q96J25, Q9HB23 |
| UniProt Entry Name | SYK_HUMAN |
| Gene Symbol | KARS1 |
| GeneID | 3735 |
| OMIM | 601421 |
| HGNC | 6215 |
| KEGG | hsa:3735 |
| Ensembl | ENSG00000065427 |
| String | 9606.ENSP00000325448 |
| Molecular Weight | 74 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |