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Potassium Voltage-Gated Channel Subfamily A Member 2 (KCNA2) Antibody
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Catalogue No: abx004811
Price:
US$203.00
(Size: 20 µl)
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KCNA2 Antibody is a Rabbit Polyclonal antibody against KCNA2. Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1.
Research Articles on Potassium Voltage-Gated Channel Subfamily A Member 2 (KCNA2)
| Target | Potassium Voltage-Gated Channel Subfamily A Member 2 (KCNA2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human KCNA2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16389 (UniProt, ExPASy) |
| UniProt Secondary AC | A0A024R0D3, A8K1Z6, Q86XG6 |
| UniProt Entry Name | KCNA2_HUMAN |
| Gene Symbol | KCNA2 |
| GeneID | 3737 |
| NCBI Accession | NP_004965.1 |
| KEGG | hsa:3737 |
| String | 9606.ENSP00000433109 |
| Molecular Weight | Calculated MW: 57 kDa Observed MW: 60 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |