Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3) Antibody

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Catalogue No: abx028230
Price: US$326.25
(Size: 80 µl)

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Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3) Antibody
Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3) Antibody

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Datasheet SDS
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes shaker, shaw, shab, and shal have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.

Target Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 239-268 amino acids from the Central region of human KCNA3.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P22001 (UniProt, ExPASy)
UniProt Secondary AC Q5VWN2
UniProt Entry Name KCNA3_HUMAN
Gene Symbol KCNA3
KEGG hsa:3738
String 9606.ENSP00000358784
Molecular Weight Calculated MW: 63.8 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse and Rat KCNA3.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3)
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