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Potassium Voltage-Gated Channel Subfamily A Regulatory Beta Subunit 3 (KCNAB3) Antibody
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Catalogue No: abx030334
Price:
US$326.25
(Size: 80 µl)
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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes shaker, shaw, shab, and shal have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member and the KCNA5 gene product assemble into a heteromultimeric A-type channel that inactivates completely and is significantly faster than other A-type Kv channels.
Research Articles on Potassium Voltage-Gated Channel Subfamily A Regulatory Beta Subunit 3 (KCNAB3)
| Target | Potassium Voltage-Gated Channel Subfamily A Regulatory Beta Subunit 3 (KCNAB3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 176-204 amino acids from the Central region of human KCNAB3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O43448 (UniProt, ExPASy) |
| UniProt Secondary AC | Q4VAW0 |
| UniProt Entry Name | KCAB3_HUMAN |
| Gene Symbol | KCNAB3 |
| KEGG | hsa:9196 |
| String | 9606.ENSP00000302719 |
| Molecular Weight | Calculated MW: 43.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |