Potassium Voltage-Gated Channel Subfamily D Member 1 (KCND1) Antibody

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes shaker, shaw, shab, and shal have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This gene is expressed at moderate levels in all tissues analyzed, with lower levels in skeletal muscle.

Target	Potassium Voltage-Gated Channel Subfamily D Member 1 (KCND1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 118-147 amino acids from the N-terminal region of human KCND1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NSA2 (UniProt, ExPASy)
UniProt Secondary AC	A6NEF1, B2RCG0, O75671
UniProt Entry Name	KCND1_HUMAN
Gene Symbol	KCND1
String	9606.ENSP00000218176
Molecular Weight	Calculated MW: 71.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Cow KCND1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Potassium Voltage-Gated Channel Subfamily D Member 1 (KCND1)

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