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Potassium Voltage-Gated Channel Subfamily H Member 1 (KCNH1) Antibody
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Catalogue No: abx005087
Price:
US$203.00
(Size: 20 µl)
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KCNH1 Antibody is a Rabbit Polyclonal antibody against KCNH1. Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
Research Articles on Potassium Voltage-Gated Channel Subfamily H Member 1 (KCNH1)
| Target | Potassium Voltage-Gated Channel Subfamily H Member 1 (KCNH1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 813-962 of human KCNH1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O95259 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AQ26, O76035, Q14CL3 |
| UniProt Entry Name | KCNH1_HUMAN |
| Gene Symbol | KCNH1 |
| GeneID | 3756 |
| NCBI Accession | NP_002229.1 |
| KEGG | hsa:3756 |
| String | 9606.ENSP00000271751 |
| Molecular Weight | Calculated MW: 111 kDa Observed MW: 111 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |