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Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) Antibody
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Catalogue No: abx002160
Price:
US$348.00
(Size: 60 µl)
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KCNH2 Antibody is a Rabbit Polyclonal antibody against KCNH2. This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1.
Research Articles on Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2)
| Target | Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human KCNH2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12809 (UniProt, ExPASy) |
| UniProt Entry Name | KCNH2_HUMAN |
| Gene Symbol | KCNH2 |
| GeneID | 3757 |
| NCBI Accession | NP_000229.1 |
| KEGG | hsa:3757 |
| String | 9606.ENSP00000262186 |
| Molecular Weight | Calculated MW: 60 kDa/90 kDa/97 kDa/115 kDa/121 kDa/126 kDa Observed MW: 148 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |