Potassium Voltage-Gated Channel Subfamily J Member 2 (KCNJ2) Antibody

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. This protein is an integral membrane protein and inward-rectifier type potassium channel. This protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is racterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.

Target	Potassium Voltage-Gated Channel Subfamily J Member 2 (KCNJ2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 401-427 amino acids from the C-terminal region of human KCNJ2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P63252 (UniProt, ExPASy)
UniProt Secondary AC	O15110, P48049
UniProt Entry Name	KCNJ2_HUMAN
KEGG	hsa:3759
String	9606.ENSP00000243457
Molecular Weight	Calculated MW: 48.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat, Cow, Pig, Chicken and Rabbit KCNJ2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Potassium Voltage-Gated Channel Subfamily J Member 2 (KCNJ2)

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