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Kelch Like ECH Associated Protein 1 (KEAP1) Antibody
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Catalogue No: abx012055
Price:
US$427.75
(Size: 100 µl)
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This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Research Articles on Kelch Like ECH Associated Protein 1 (KEAP1)
| Target | Kelch Like ECH Associated Protein 1 (KEAP1) |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IF/ICC: 1/50, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human KEAP1 (AA: 380-624) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14145 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KPD5, Q6LEP0, Q8WTX1, Q9BPY9 |
| UniProt Entry Name | KEAP1_HUMAN |
| GeneID | 9817 |
| KEGG | hsa:9817 |
| String | 9606.ENSP00000171111 |
| Molecular Weight | 69.7 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |