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Kelch Like ECH Associated Protein 1 (KEAP1) Antibody
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Catalogue No: abx001504
Price:
US$174.00
(Size: 20 µl)
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This product is currently in development. The lead time for this product may be several months. Please contact us at [email protected] for an updated lead time before purchasing this product. KEAP1 Antibody is a Rabbit Polyclonal antibody against KEAP1. This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Research Articles on Kelch Like ECH Associated Protein 1 (KEAP1)
| Target | Kelch Like ECH Associated Protein 1 (KEAP1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 320-510 of human KEAP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14145 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KPD5, Q6LEP0, Q8WTX1, Q9BPY9 |
| UniProt Entry Name | KEAP1_HUMAN |
| Gene Symbol | KEAP1 |
| GeneID | 9817 |
| NCBI Accession | NP_036421.2 |
| KEGG | hsa:9817 |
| String | 9606.ENSP00000171111 |
| Molecular Weight | Calculated MW: 70 kDa Observed MW: 60-64 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |