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KH-Type Splicing Regulatory Protein (KHSRP) Antibody
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Catalogue No: abx033030
Price:
US$326.25
(Size: 80 µl)
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KHSRP binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). It is a part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. It may interact with single-stranded DNA from the far-upstream element (FUSE) and activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Research Articles on KH-Type Splicing Regulatory Protein (KHSRP)
| Target | KH-Type Splicing Regulatory Protein (KHSRP) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human KHSRP. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q92945 (UniProt, ExPASy) |
| UniProt Secondary AC | O00301, Q59EZ9, Q5U4P6, Q9UNT5, Q9UQH5 |
| UniProt Entry Name | FUBP2_HUMAN |
| KEGG | hsa:8570 |
| String | 9606.ENSP00000381216 |
| Molecular Weight | Calculated MW: 73.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Chicken KHSRP. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |