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Kinesin-Associated Protein 3 (KIFAP3) Antibody
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Catalogue No: abx003385
Price:
US$203.00
(Size: 20 µl)
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KIFAP3 Antibody is a Rabbit Polyclonal antibody against KIFAP3. The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.
Research Articles on Kinesin-Associated Protein 3 (KIFAP3)
| Target | Kinesin-Associated Protein 3 (KIFAP3) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human KIFAP3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q92845 (UniProt, ExPASy) |
| UniProt Secondary AC | B1AKU4, B1AKU5, B2RDL1, B7Z8A3, F5H591, Q8NHU7, Q9H416 |
| UniProt Entry Name | KIFA3_HUMAN |
| Gene Symbol | KIFAP3 |
| GeneID | 22920 |
| NCBI Accession | NP_055785.2 |
| KEGG | hsa:22920 |
| String | 9606.ENSP00000354560 |
| Molecular Weight | Calculated MW: 91 kDa Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |