Kininogen 1 (KNG1) Antibody

Kininogen 1 (KNG1) Antibody is a Rabbit Polyclonal antibody for the detection of KNG1.

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Target	Kininogen 1 (KNG1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Kininogen-1
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P01042 (UniProt, ExPASy)
UniProt Secondary AC	A8K474, B2RCR2, C9JEX1, P01043, Q53EQ0, Q6PAU9, Q7M4P1
UniProt Entry Name	KNG1_HUMAN
Gene Symbol	KNG1
GeneID	3827
OMIM	228960
HGNC	6383
KEGG	hsa:3827
Ensembl	ENSG00000113889
String	9606.ENSP00000265023
Molecular Weight	Observed MW: 68 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Kininogen 1 (KNG1)

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