Calcium And Integrin-Binding Family Member 2 (CIB2) Antibody

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Catalogue No: abx033921
Price: US$326.25
(Size: 80 µl)
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Calcium And Integrin-Binding Family Member 2 (CIB2) Antibody
Calcium And Integrin-Binding Family Member 2 (CIB2) Antibody Calcium And Integrin-Binding Family Member 2 (CIB2) Antibody

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Datasheet SDS
DNA-dependent protein kinases (DNA-PK) play a role in the repair of double-strand DNA breaks and in the process of V (D) J recombination during lymphoid development. By EST database searching for sequences homologous to the DNA-PK gene KIP/CIB and 5-prime RACE, Seki, N et al. isolated a full-length cDNA, which they designated as KIP2, from a human fetal brain cDNA library. KIP2 encodes a deduced 187-amino acid protein with a predicted molecular mass of 22 kD. The KIP2 protein shares 46%, 39%, and 30% sequence identity with the calcium-binding proteins KIP/CIB, calcineurin B and calmodulin respectively. KIP2 contains two EF-hand motifs and a helix-loop-helix motif involved in coordinating the calcium ion, indicating that KIP2 may also bind calcium. KIP2 is ubiquitously expressed in various human tissues.

Target Calcium And Integrin-Binding Family Member 2 (CIB2)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human KIP2.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O75838 (UniProt, ExPASy)
UniProt Secondary AC B4DDF0, H0YM71, Q05BT6
UniProt Entry Name CIB2_HUMAN
KEGG hsa:10518
String 9606.ENSP00000258930
Molecular Weight Calculated MW: 21.6 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Calcium And Integrin-Binding Family Member 2 (CIB2)
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