KIT (pY730) Antibody

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	KIT (pY730)
Clonality	Polyclonal
Target Modification	Tyr730
Modification	Phosphorylation
Reactivity	Human
Tested Applications	ELISA, DB
Host	Rabbit
Recommended dilutions	DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y730 of human KIT.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P10721 (UniProt, ExPASy)
UniProt Secondary AC	B5A956, D5LXN2, D5M931, F5H8F8, Q6IQ28, Q99662, Q9UM99
Molecular Weight	Calculated MW: 110 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow and Pig KIT.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on KIT (pY730)

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