Krueppel-Like Factor 4 (KLF4) Antibody

Kruppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.

Target	Krueppel-Like Factor 4 (KLF4)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 20-53 amino acids from the N-terminal region of human KLF4.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43474 (UniProt, ExPASy)
UniProt Entry Name	KLF4_HUMAN
Gene Symbol	KLF4
GeneID	9314
OMIM	602253
NCBI Accession	NP_004226.3
HGNC	6348
KEGG	hsa:9314
Ensembl	ENSG00000136826
String	9606.ENSP00000363804
Molecular Weight	Calculated MW: 54.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Krueppel-Like Factor 4 (KLF4)

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