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Kelch-Like Protein 12 (KLHL12) Antibody
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Catalogue No: abx029451
Price:
US$326.25
(Size: 80 µl)
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Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
Research Articles on Kelch-Like Protein 12 (KLHL12)
| Target | Kelch-Like Protein 12 (KLHL12) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human KLHL12. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q53G59 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NEN8, B7Z7B8, Q9HBX5 |
| UniProt Entry Name | KLH12_HUMAN |
| Gene Symbol | KLHL12 |
| GeneID | 59349 |
| OMIM | 614522 |
| HGNC | 19360 |
| KEGG | hsa:59349 |
| Ensembl | ENSG00000117153 |
| String | 9606.ENSP00000356230 |
| Molecular Weight | Calculated MW: 63.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Rat, Cow, Zebrafish and Xenopus KLHL12. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |