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Klotho (KL) Antibody
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Catalogue No: abx031812
Price:
US$326.25
(Size: 80 µl)
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Klotho is a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.
Research Articles on Klotho (KL)
| Target | Klotho (KL) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 986-1012 amino acids from the C-terminal region of human Klotho. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UEF7 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5VZ95, Q96KV5, Q96KW5, Q9UEI9, Q9Y4F0 |
| UniProt Entry Name | KLOT_HUMAN |
| NCBI Accession | NP_004786.2 |
| String | 9606.ENSP00000369442 |
| Enzyme Commission Number | EC 3.2.1.31 EC 3.2.1 |
| Molecular Weight | Calculated MW: 116 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |