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NKG2-A/NKG2-B Type II Integral Membrane Protein (KLRC1) Antibody
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Catalogue No: abx034035
Price:
US$326.25
(Size: 50 µl)
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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.
Research Articles on NKG2-A/NKG2-B Type II Integral Membrane Protein (KLRC1)
| Target | NKG2-A/NKG2-B Type II Integral Membrane Protein (KLRC1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/25, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 180-206 amino acids from the C-terminal region of human KLRC1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P26715 (UniProt, ExPASy) |
| UniProt Entry Name | NKG2A_HUMAN |
| Gene Symbol | KLRC1 |
| NCBI Accession | NP_002250.1 NP_015567.1 NP_998822.1 NP_998823.1 |
| KEGG | hsa:3821 |
| String | 9606.ENSP00000438038 |
| Molecular Weight | Calculated MW: 26.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |