Kininogen 1 (KNG1) Antibody

This gene uses alternative splicing to generate two different proteins high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Target	Kininogen 1 (KNG1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 138-166 amino acids from the N-terminal region of human KNG1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01042 (UniProt, ExPASy)
UniProt Secondary AC	A8K474, B2RCR2, C9JEX1, P01043, Q53EQ0, Q6PAU9, Q7M4P1
UniProt Entry Name	KNG1_HUMAN
Gene Symbol	KNG1
KEGG	hsa:3827
String	9606.ENSP00000265023
Molecular Weight	Calculated MW: 72 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Kininogen 1 (KNG1)

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