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GTPase KRas (KRAS) Antibody
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Catalogue No: abx001104
Price:
US$203.00
(Size: 20 µl)
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KRAS Antibody is a Rabbit Polyclonal antibody against KRAS. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.
Research Articles on GTPase KRas (KRAS)
| Target | GTPase KRas (KRAS) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 30-189 of human KRAS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P01116 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K8Z5, B0LPF9, P01118, Q96D10 |
| UniProt Entry Name | RASK_HUMAN |
| Gene Symbol | KRAS |
| GeneID | 3845 |
| NCBI Accession | NP_203524.1 |
| KEGG | hsa:3845 |
| String | 9606.ENSP00000256078 |
| Molecular Weight | Calculated MW: 22 kDa Observed MW: 21 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 3.01 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |