Keratin, Type II Cytoskeletal 3 (KRT3) Antibody

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Target	Keratin, Type II Cytoskeletal 3 (KRT3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 414-441 amino acids from the Central region of human KRT3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P12035 (UniProt, ExPASy)
UniProt Secondary AC	A6NIS2, Q701L8
UniProt Entry Name	K2C3_HUMAN
KEGG	hsa:3850
String	9606.ENSP00000413479
Molecular Weight	Calculated MW: 64.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Keratin, Type II Cytoskeletal 3 (KRT3)

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