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Keratin, Type II Cytoskeletal 5 (KRT5) Antibody
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Catalogue No: abx002052
Price:
US$217.50
(Size: 20 µl)
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KRT5 Antibody is a Rabbit Polyclonal antibody against KRT5. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Research Articles on Keratin, Type II Cytoskeletal 5 (KRT5)
| Target | Keratin, Type II Cytoskeletal 5 (KRT5) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cytokeratin 5 (KRT5). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P13647 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6PI71, Q6UBJ0, Q8TA91 |
| UniProt Entry Name | K2C5_HUMAN |
| Gene Symbol | KRT5 |
| GeneID | 3852 |
| NCBI Accession | NP_000415.2 |
| KEGG | hsa:3852 |
| String | 9606.ENSP00000252242 |
| Molecular Weight | Calculated MW: 62 kDa Observed MW: 62 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |