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Keratin 6A (KRT6A) Antibody
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Catalogue No: abx029191
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq].
Research Articles on Keratin 6A (KRT6A)
| Target | Keratin 6A (KRT6A) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human KRT6A. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P02538 (UniProt, ExPASy) |
| UniProt Secondary AC | A4QPC1, P48667, Q08AR4, Q6NT67, Q96CL4 |
| UniProt Entry Name | K2C6A_HUMAN |
| Gene Symbol | KRT6A |
| KEGG | hsa:3853 |
| String | 9606.ENSP00000369317 |
| Molecular Weight | Calculated MW: 60 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |