Keratin, Type II Cytoskeletal 8 (KRT8) Antibody

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Catalogue No: abx000965
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
KRT8 Antibody is a Rabbit Polyclonal antibody against KRT8. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Target Keratin, Type II Cytoskeletal 8 (KRT8)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/2000 - 1/4000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-483 of human Cytokeratin 8 (KRT8).
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05787 (UniProt, ExPASy)
UniProt Entry Name K2C8_HUMAN
Gene Symbol KRT8
GeneID 3856
NCBI Accession NP_002264.1
KEGG hsa:3856
String 9606.ENSP00000449404
Molecular Weight Calculated MW: 54 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Keratin, Type II Cytoskeletal 8 (KRT8)


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