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Keratin, Type II Cytoskeletal 8 (KRT8) Antibody
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Catalogue No: abx000965
Price:
US$203.00
(Size: 20 µl)
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KRT8 Antibody is a Rabbit Polyclonal antibody against KRT8. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Research Articles on Keratin, Type II Cytoskeletal 8 (KRT8)
| Target | Keratin, Type II Cytoskeletal 8 (KRT8) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/2000 - 1/4000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-483 of human Cytokeratin 8 (KRT8). |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P05787 (UniProt, ExPASy) |
| UniProt Entry Name | K2C8_HUMAN |
| Gene Symbol | KRT8 |
| GeneID | 3856 |
| NCBI Accession | NP_002264.1 |
| KEGG | hsa:3856 |
| String | 9606.ENSP00000449404 |
| Molecular Weight | Calculated MW: 54 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |