Krueppel-Like Factor 4 (KLF4) Antibody

Krueppel-Like Factor 4 (KLF4) Antibody is a Rabbit Polyclonal antibody for the detection of KLF4.

This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target	Krueppel-Like Factor 4 (KLF4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Kruppel-like factor 4 (gut)
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	O43474 (UniProt, ExPASy)
UniProt Entry Name	KLF4_HUMAN
Gene Symbol	KLF4
GeneID	9314
OMIM	602253
HGNC	6348
KEGG	hsa:9314
Ensembl	ENSG00000136826
String	9606.ENSP00000363804
Molecular Weight	Observed MW: 50 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Krueppel-Like Factor 4 (KLF4)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue