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Krueppel-Like Factor 4 (KLF4) Antibody
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Catalogue No: abx239975
Price:
US$406.00
(Size: 100 µg)
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Krueppel-Like Factor 4 (KLF4) Antibody is a Rabbit Polyclonal antibody for the detection of KLF4. This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Krueppel-Like Factor 4 (KLF4)
| Target | Krueppel-Like Factor 4 (KLF4) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/200 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Kruppel-like factor 4 (gut) |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Validity | 12 months. |
| UniProt Primary AC | O43474 (UniProt, ExPASy) |
| UniProt Entry Name | KLF4_HUMAN |
| Gene Symbol | KLF4 |
| GeneID | 9314 |
| OMIM | 602253 |
| HGNC | 6348 |
| KEGG | hsa:9314 |
| Ensembl | ENSG00000136826 |
| String | 9606.ENSP00000363804 |
| Molecular Weight | Observed MW: 50 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | This product is for research use only. |