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Kinase Suppressor of Ras 2 (KSR2) Antibody
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Catalogue No: abx026265
Price:
US$326.25
(Size: 80 µl)
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Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
Research Articles on Kinase Suppressor of Ras 2 (KSR2)
| Target | Kinase Suppressor of Ras 2 (KSR2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 603-638 amino acids from the C-terminal region of human KSR2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q6VAB6 (UniProt, ExPASy) |
| UniProt Secondary AC | A0PJT2, Q3B828, Q8N775 |
| UniProt Entry Name | KSR2_HUMAN |
| Gene Symbol | KSR2 |
| KEGG | hsa:283455 |
| String | 9606.ENSP00000389715 |
| Molecular Weight | Calculated MW: 108 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |