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L-2-Hydroxyglutarate Dehydrogenase (L2HGDH) Antibody
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Catalogue No: abx025654
Price:
US$326.25
(Size: 80 µl)
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This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.
Research Articles on L-2-Hydroxyglutarate Dehydrogenase (L2HGDH)
| Target | L-2-Hydroxyglutarate Dehydrogenase (L2HGDH) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 132-159 amino acids from the Central region of human L2HGDH. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9H9P8 (UniProt, ExPASy) |
| UniProt Secondary AC | Q9BRR1 |
| UniProt Entry Name | L2HDH_HUMAN |
| Gene Symbol | L2HGDH |
| String | 9606.ENSP00000267436 |
| Molecular Weight | Calculated MW: 50.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |