Lamin-B Receptor (LBR) Antibody

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Catalogue No: abx004188
Price: US$217.50
(Size: 20 µl)

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Datasheet SDS
LBR Antibody is a Rabbit Polyclonal antibody against LBR. The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Target Lamin-B Receptor (LBR)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IF/ICC
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-211 of human LBR.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q14739 (UniProt, ExPASy)
UniProt Secondary AC B2R5P3, Q14740, Q53GU7, Q59FE6
UniProt Entry Name LBR_HUMAN
Gene Symbol LBR
GeneID 3930
NCBI Accession NP_002287.2
KEGG hsa:3930
String 9606.ENSP00000339883
Molecular Weight Calculated MW: 71 kDa
Observed MW: 68 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Lamin-B Receptor (LBR)


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