Lymphocyte Cytosolic Protein 1 (LCP1) Antibody

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.

Target	Lymphocyte Cytosolic Protein 1 (LCP1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 306-335 amino acids from the Central region of human LCP1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P13796 (UniProt, ExPASy)
UniProt Secondary AC	B2R613, B4DUA0, Q5TBN4
UniProt Entry Name	PLSL_HUMAN
KEGG	hsa:3936
String	9606.ENSP00000381581
Molecular Weight	Calculated MW: 70.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse LCP1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Lymphocyte Cytosolic Protein 1 (LCP1)

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