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Lymphoid Enhancer Binding Factor 1 (LEF1) Antibody
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Catalogue No: abx026579
Price:
US$326.25
(Size: 80 µl)
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This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
Research Articles on Lymphoid Enhancer Binding Factor 1 (LEF1)
| Target | Lymphoid Enhancer Binding Factor 1 (LEF1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human LEF1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UJU2 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DG38, B7Z8E2, E9PDK3, Q3ZCU4, Q9HAZ0 |
| UniProt Entry Name | LEF1_HUMAN |
| Gene Symbol | LEF1 |
| String | 9606.ENSP00000265165 |
| Molecular Weight | Calculated MW: 44.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat LEF1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |